BioTech Mag Search: Biosynthesis
Biosynthesis and transfer of 2-acetamido-4-methylamino-l-fucose to the core-lipid A in Bordetella pertussis
Abstract The trisaccharide unit in lipopolysaccharide of Bordetella pertussis is important for immune recognition, but how the rare sugar 2-acetamido-4-methylamino-fucose in...
5 days ago - Springer
Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system
Ε-Poly-L-lysine is a natural and safe food preservative that is mainly produced by filamentous and aerobic bacteria Streptomyces albulus. During ε-PL biosynthesis, a large...
8 days ago - Microbial Cell Factories
Efficient biosynthesis of resveratrol via combining phenylalanine and tyrosine pathways in Saccharomyces cerevisiae
Resveratrol is a commercially available stilbenoid widely used as dietary supplements, functional food ingredients, and cosmetic ingredients due to its diverse physiological...
13 days ago - Microbial Cell Factories
A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae
Owing to the Crabtree effect, Saccharomyces cerevisiae produces a large amount of ethanol in the presence of oxygen and excess glucose, leading to a loss of carbon for the...
17 days ago - Biotechnology for Biofuels
Structural Basis for Substrate Binding and Catalytic Mechanism of the Key Enzyme VioD in the Violacein Synthesis Pathway
Abstract Violacein is a pigment synthesized by gram-negative bacteria with various biological activities such as antimicrobial, antiviral, and anticancer activities. VioD is a...
17 days ago - Wiley
Overexpression of GPS and FPS from Chrysanthemum indicum var. aromaticum resulted in modified trichome formation and terpenoid biosynthesis in tobacco
Abstract Geranyl diphosphate synthase and farnesyl diphosphate synthase catalyzes the biosynthesis of monoterpenoids and sesquiterpenoids, two key precursors for terpenoids...
18 days ago - Springer
Metabolic engineering for the biosynthesis of bis-indolylquinone terrequinone A in Escherichia coli from L-tryptophan and prenol
Terrequinone A is a bis-indolylquinone natural product with antitumor activity. Due to its unique asymmetric quinone core structure and multiple functional groups, biosynthesis...
20 days ago - Biotechnology for Biofuels
Heme biosensor-guided in vivo pathway optimization and directed evolution for efficient biosynthesis of heme
Heme has attracted much attention because of its wide applications in medicine and food. The products of genes hemBCDEFY convert 5-aminolevulinic acid to protoporphyrin IX ;...
21 days ago - Biotechnology for Biofuels
Mapping competitive pathways to terpenoid biosynthesis in Synechocystis sp. PCC 6803 using an antisense RNA synthetic tool
Synechocystis sp. PCC 6803 utilizes pyruvate and glyceraldehyde 3-phosphate via the methylerythritol 4-phosphate pathway for the biosynthesis of terpenoids. Considering the...
27 days ago - Microbial Cell Factories
Identification of RimR2 as a positive pathway-specific regulator of rimocidin biosynthesis in Streptomyces rimosus M527
Streoptomyces rimosus M527 is a producer of the polyene macrolide rimocidin which shows activity against various plant pathogenic fungi. Notably, the regulatory mechanisms...
1 month ago - Microbial Cell Factories
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
New UN Report: Limiting Global Warming to 1.5 Degrees Celsius Requires Deep...
Ionis accounces FDA advisory committee voted unanimously for a potential...
If approved, tofersen will be the first treatment targeting a genetic cause of ALS and the next marketed Ionis-discovered antisense medicine FDA decision expected by April 25...
Director/Senior Director, Human Resources - Recludix Pharma - San Diego, CA
Identify innovative solutions and compelling training to support Recludix employees' leadership and professional growth. $180,000 - $220,000 a yearFrom Recludix...
Sr. Research Scientist I, Formulation Process Development - Gilead Sciences...
Lead the design and execution of development studies that employ a variety of analytical techniques, including HPLC, capillary electrophoresis, spectroscopy,...
School of Medicine Student on Finding Love as a Trans Woman
Like most people her age, Daniella McDonald spent a lot of time talking with friends about relationships and using dating apps. But, as a transgender woman, the experience for...
DrTalks Presents The Reverse Inflammaging Body and Mind Longevity Medicine...
CARLSBAD, Calif., March 22, 2023 /PRNewswire/ - DrTalks.com is pleased to announce the upcoming Reverse Inflammaging Body and Mind Longevity Medicine Summit from April 25th to...
Active targeting schemes for nano-drug delivery systems in osteosarcoma...
Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's lives and increases their economic burden. Conventional chemotherapy drugs achieve...
UFGI Faculty Spotlight - Looking at Human Neurological Disorders through...
Observing group-living animals with drones and computer vision
A drone is flying over a herd of plains zebras in central Kenya. It is flying quite high so that the animals are not bothered by it. These zebras are really interesting for...
New method shrinks 3D images of cells for faster storage and retrieval
Single-cell analysis is a powerful biomedical technique used in various fields of biology and medicine to identify rare cell populations, track cell development and...