BioTech Mag Search: Brain
Technique allows mapping of epigenetic information in single cells at scale
Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique...
15 hours ago - Phys
Huntington's Disease: 2 Steps Backward, 1 Step Forward
Last week's DNA Science post considered the ebb and flow of treatment possibilities for Alzheimer's disease. This week, it's Huntington's disease. Like Alzheimer's, the less...
4 days ago - DNA Science
Conrad Prebys Foundation provides $3 million for pediatric brain cancer research
Conrad Prebys was an extraordinary man and a passionate philanthropist. Today, his generosity extends beyond his life through the Conrad Prebys Foundation. This year, the...
5 days ago - San Diego Biotechnology
Biocept to Host Key Opinion Leader Webinar to Discuss Its CSF Assay for the Diagnosis of Cancer Involving the Central Nervous System
SAN DIEGO--Biocept, Inc. will host a webinar featuring leading neuro-oncologists to discuss the use of the Company's proprietary cerebrospinal fluid assay for diagnosing and...
5 days ago - San Diego Biotechnology
New Blueprint of Brain Connections Reveals Extensive Reach of Central Regulator
UC San Diego researchers have generated a new map of brain connectivity from a part of the brain called the basal ganglia, a hub for regulating motor and behavior functions...
7 days ago - San Diego Biotechnology
Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration
Abstract Neurons produced by reprogramming of other cell types are used to study cellular mechanisms of age-related neurodegenerative diseases. To model Alzheimer's disease and...
10 days ago - Springer
Aging-Dependent Mitophagy Dysfunction in Alzheimer's Disease
Abstract Alzheimer's disease is the most common late-onset dementia characterized by the deposition of extracellular amyloid plaques and formation of intracellular...
10 days ago - Springer - 2 articles
Modified Snake α-Neurotoxin Averts β-Amyloid Binding to α7 Nicotinic Acetylcholine Receptor and Reverses Cognitive Deficits in Alzheimer's Disease Mice
Abstract Alzheimer's disease is the most common cause of senile dementia and one of the greatest medical, social, and economic challenges. According to a dominant theory...
10 days ago - Springer - 2 articles
Distinct Parkinson's Disease Symptoms Tied to Different Brain Pathways
Neurobiologists have found that identifiable brain pathways are linked with specific debilitating symptoms of Parkinson's disease. The findings could help form the basis for...
10 days ago - San Diego Biotechnology
Comorbidity between Alzheimer's disease and major depression: a behavioural and transcriptomic characterization study in mice
Abstract Background Major depression is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer's disease. Despite both...
11 days ago - Springer
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Colored Network Motif Analysis by Dynamic Programming Approach: An...
Network motifs are subgraphs of a network which are found with significantly higher frequency than that expected in similar random networks. Motifs are small building blocks of...
Improve the Resolution and Parallel Performance of the Three-Dimensional...
In cryo-electron microscopy, RELION is a powerful tool for high-resolution reconstruction. Due to the complicated imaging procedure and the heterogeneity of particles, some of...
IPhosH-PseAAC: Identify Phosphohistidine Sites in Proteins by Blending...
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is responsible for various biological functions such as protein degradation, intracellular...
MCHMDA:Predicting Microbe-Disease Associations Based on Similarities and...
With the development of high-through sequencing technology and microbiology, many studies have evidenced that microbes are associated with human diseases, such as obesity...
MGRFE: Multilayer Recursive Feature Elimination Based on an Embedded Genetic...
Microarray gene expression data have become a topic of great interest for cancer classification and for further research in the field of bioinformatics. Nonetheless, due to the...
ANCA: Alignment-Based Network Construction Algorithm
Dynamic biological networks model changes in the network topology over time. However, often the topologies of these networks are not available at specific time points. Existing...
Bayesian Inference in Y-Linked Two-Sex Branching Processes with Mutations...
A Y-linked two-sex branching process with mutations and blind choice of males is a suitable model for analyzing the evolution of the number of carriers of a Y-linked allele and...
CNV IFTV: An Isolation Forest and Total Variation-Based Detection of CNVs...
Accurate detection of copy number variations from short-read sequencing data is challenging due to the uneven distribution of reads and the unbalanced amplitudes of gains and...
Vaccines: Herd Immunity, Passports, Reaching the Underserved
As the COVID-19 vaccinations roll out with increasing speed, questions are now arising about herd immunity, the need to reach underserved populations, and a proposed passport...
Computational methods for chromosome-scale haplotype reconstruction
High-quality chromosome-scale haplotype sequences of diploid genomes, polyploid genomes, and metagenomes provide important insights into genetic variation associated with...