BioTech Mag Search: Drug
Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells
The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells has provided a foundation for in vitro human disease modelling, drug development and...
1 day ago - Genome Biology
DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks
Knowledge on the molecular targets of diseases and drugs is crucial for elucidating disease pathogenesis and mechanism of action of drugs, and for driving drug discovery and...
1 day ago - BMC Bioinformatics
Senior Research Associate/Scientist - Plex Pharmaceuticals - San Diego, CA
Strong organizational skills and attention to detail. The successful candidate will contribute to drug discovery efforts by performing compound screening in...From Plex...
2 days ago - San Diego Biotechnology - 5 articles
New method facilitates development of antibody-based drugs
In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers have developed a new, efficient method based on the...
2 days ago - ScienceDaily
Study: Combined liver-cytokine humanization rescues circulating red blood cells for testing drugs
In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell...
2 days ago - Phys
Infusion Mechanisms in Brain White Matter and its Dependence of Microstructure: An Experimental Study of Hydraulic Permeability
The limited understanding of solute transport in brain white matter tissue has hindered optimisation of infusion-based drug delivery therapies. This paper describes the first...
2 days ago - EMBS
Design, Synthesis and Evaluation of Antimicrobial Database-Derived Peptides Against Drug-Resistant Gram-Positive and Gram-Negative Pathogens
Abstract Bacterial drug resistance has become a serious problem worldwide as a consequence of long-term use and misuse of antibiotics. Current research trends indicate the...
2 days ago - Springer
Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach
Abstract Drug-induced liver injury presentation varies biochemically and histologically. Certain drugs present quite consistent injury patterns, i.e., DILI signatures. In...
3 days ago - Springer
Ajinomoto Bio-Pharma Services: Director, Drug Product Manufacturing
Ajinomoto Bio-Pharma Services: We are currently seeking a Director of Drug Product Manufacturing to lead clinical and commercial drug product manufacturing operations. 92121...
3 days ago - San Diego Biotechnology - 3 articles
DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks
Abstract Background Knowledge on the molecular targets of diseases and drugs is crucial for elucidating disease pathogenesis and mechanism of action of drugs, and for driving...
3 days ago - Springer - 2 articles
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The headlines of BioTech Mag
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Impact of media components from different suppliers on enterokinase...
The aim of this study was to provide an information about the homogeneity on the level of enterokinase productivity in P. pastoris depending on different suppliers of the media...
A novel seven-gene panel predicts the sensitivity and prognosis of head and...
Abstract Purpose The aim of the study is to identify a reliable gene panel to predict the prognosis of HNSCC patients by integrated genomic analysis. Methods Co-expression gene...
A mathematical model of COVID-19 transmission between frontliners and the...
Abstract The number of COVID-19 cases is continuously increasing in different countries including the Philippines. It is estimated that the basic reproduction number of...
TMT-Based Quantitative Proteomic Revealed Metabolic Changes of Jasmonic Acid...
Abstract Malus baccata Borkh. is widely used as an apple rootstock in northern China. Previous studies have shown that jasmonic acid can alleviate the oxidative damage in M...
An efficient system for intestinal on-site butyrate production using novel...
Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of...
Physiological and transcriptional response to drought stress among bioenergy...
Miscanthus is a commercial lignocellulosic biomass crop owing to its high biomass productivity, resilience and photosynthetic capacity at low temperature. These qualities make...
Identification of a novel glycerophosphodiester phosphodiesterase from...
Abstract Diphenyl phosphate has been increasingly detected in environmental samples, posing a potential hazard to humans and other organisms and arousing concern regarding its...
Species and geographic specificity between endophytic fungi and host...
Abstract This study was aimed to investigate whether host plant species and lifestyles, and environmental conditions in the desert affect endophytic fungi composition...
SomatoSim: precision simulation of somatic single nucleotide variants
Somatic single nucleotide variants have gained increased attention because of their role in cancer development and the widespread use of high-throughput sequencing techniques...
In silico determination of nitrogen metabolism in microbes from extreme...
Abstract The acid ponds of the Danakil Depression in northern Ethiopia are polyextreme environments that exceed the normal physicochemical limits of pH, salinity, ion content...