BioTech Mag Search: Drugs
Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells
The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells has provided a foundation for in vitro human disease modelling, drug development and...
18 hours ago - Genome Biology
DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks
Knowledge on the molecular targets of diseases and drugs is crucial for elucidating disease pathogenesis and mechanism of action of drugs, and for driving drug discovery and...
1 day ago - BMC Bioinformatics
Senior Research Associate/Scientist - Plex Pharmaceuticals - San Diego, CA
Strong organizational skills and attention to detail. The successful candidate will contribute to drug discovery efforts by performing compound screening in...From Plex...
1 day ago - San Diego Biotechnology - 5 articles
New method facilitates development of antibody-based drugs
In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers have developed a new, efficient method based on the...
1 day ago - ScienceDaily
Study: Combined liver-cytokine humanization rescues circulating red blood cells for testing drugs
In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell...
1 day ago - Phys
Infusion Mechanisms in Brain White Matter and its Dependence of Microstructure: An Experimental Study of Hydraulic Permeability
The limited understanding of solute transport in brain white matter tissue has hindered optimisation of infusion-based drug delivery therapies. This paper describes the first...
2 days ago - EMBS
Design, Synthesis and Evaluation of Antimicrobial Database-Derived Peptides Against Drug-Resistant Gram-Positive and Gram-Negative Pathogens
Abstract Bacterial drug resistance has become a serious problem worldwide as a consequence of long-term use and misuse of antibiotics. Current research trends indicate the...
2 days ago - Springer
Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach
Abstract Drug-induced liver injury presentation varies biochemically and histologically. Certain drugs present quite consistent injury patterns, i.e., DILI signatures. In...
2 days ago - Springer
Ajinomoto Bio-Pharma Services: Director, Drug Product Manufacturing
Ajinomoto Bio-Pharma Services: We are currently seeking a Director of Drug Product Manufacturing to lead clinical and commercial drug product manufacturing operations. 92121...
2 days ago - San Diego Biotechnology - 3 articles
DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks
Abstract Background Knowledge on the molecular targets of diseases and drugs is crucial for elucidating disease pathogenesis and mechanism of action of drugs, and for driving...
2 days ago - Springer - 2 articles
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The headlines of BioTech Mag
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Identification of a novel glycerophosphodiester phosphodiesterase from...
Abstract Diphenyl phosphate has been increasingly detected in environmental samples, posing a potential hazard to humans and other organisms and arousing concern regarding its...
Species and geographic specificity between endophytic fungi and host...
Abstract This study was aimed to investigate whether host plant species and lifestyles, and environmental conditions in the desert affect endophytic fungi composition...
SomatoSim: precision simulation of somatic single nucleotide variants
Somatic single nucleotide variants have gained increased attention because of their role in cancer development and the widespread use of high-throughput sequencing techniques...
In silico determination of nitrogen metabolism in microbes from extreme...
Abstract The acid ponds of the Danakil Depression in northern Ethiopia are polyextreme environments that exceed the normal physicochemical limits of pH, salinity, ion content...
A novel transcript variant of human G-protein coupled estrogen receptor
Abstract The G-protein coupled estrogen receptor mediates short-term non-genomic effects of estrogen in diverse cell types and tissues. According to the NCBI nucleotide...
Development of a Targeted Integration Chinese Hamster Ovary Host Directly...
Abstract Cell line development by random integration can be labor intensive, inconsistent and unpredictable due to uncontrolled gene integration after transfection. Unlike RI...
Transgenic plants expressing a Clostridium difficile spore antigen as an...
Abstract Gastrointestinal infections caused by Clostridium difficile lead to significant impact in terms of morbidity and mortality, causing from mild symptoms, such as a...
Prebiotic peptides, their formation, fermentation in the gut and health...
Abstract Prebiotics can be synthesized from sources other than dietary fibres, such as proteins. The proteins, when processed into peptides have healthful or deleterious...
GC-MS analysis and molecular docking of bioactive compounds of Camellia...
Abstract The methanol extract of Camellia sinensis and acetone extract of Camellia assamica were subjected to the thin layer chromatography to separate the bioactive compounds...
The wind of change in the management of autosomal dominant polycystic kidney...
Abstract Significant progress has been made in understanding the genetic basis of autosomal dominant polycystic kidney disease , quantifying disease manifestations in children...