BioTech Mag Search: Gene
MGRFE: Multilayer Recursive Feature Elimination Based on an Embedded Genetic Algorithm for Cancer Classification
Microarray gene expression data have become a topic of great interest for cancer classification and for further research in the field of bioinformatics. Nonetheless, due to the...
1 hour ago - IEEE/ACM
DeepDSC: A Deep Learning Method to Predict Drug Sensitivity of Cancer Cell Lines
High-throughput screening technologies have provided a large amount of drug sensitivity data for a panel of cancer cell lines and hundreds of compounds. Computational...
1 hour ago - IEEE/ACM - 2 articles
ANCA: Alignment-Based Network Construction Algorithm
Dynamic biological networks model changes in the network topology over time. However, often the topologies of these networks are not available at specific time points. Existing...
1 hour ago - IEEE/ACM
A benchmark for RNA-seq deconvolution analysis under dynamic testing environments
Deconvolution analyses have been widely used to track compositional alterations of cell types in gene expression data. Although a large number of novel methods have been...
5 hours ago - Genome Biology
Senior/Principle Scientist, Gene Therapy Bioassay Development - Locana - San Diego, CA
PhD in Biological Sciences or relevant field plus minimum of 10 years of experience in the biotechnology or pharma industry, with a primary focus on analytical...From Locana...
6 hours ago - San Diego Biotechnology - 6 articles
Researchers call for greater awareness of unintended consequences of CRISPR gene editing
Researchers at the Francis Crick Institute have revealed that CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos...
16 hours ago - Phys
Understudied mutations have big impact on gene expression
An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable number tandem repeats that actively...
16 hours ago - Phys
For tomato genes, one plus one doesn't always make two
Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations-mutations-that affect how genes act and...
16 hours ago - Phys
Technique allows mapping of epigenetic information in single cells at scale
Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique...
16 hours ago - Phys
Emerging Molecular Tools for Engineering Phytomicrobiome
Abstract Microbial plant interaction plays a major role in the sustainability of plants. The understanding of phytomicrobiome interactions enables the gene-editing tools for...
1 day ago - Springer
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Insights into Modular Polyketide Synthase Loops Aided by Repetitive Sequences
ABSTRACT The loops of modular polyketide synthases serve diverse functions but are largely uncharacterized. They frequently contain amino acid repeats resulting from genetic...
Colored Network Motif Analysis by Dynamic Programming Approach: An...
Network motifs are subgraphs of a network which are found with significantly higher frequency than that expected in similar random networks. Motifs are small building blocks of...
Improve the Resolution and Parallel Performance of the Three-Dimensional...
In cryo-electron microscopy, RELION is a powerful tool for high-resolution reconstruction. Due to the complicated imaging procedure and the heterogeneity of particles, some of...
IPhosH-PseAAC: Identify Phosphohistidine Sites in Proteins by Blending...
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is responsible for various biological functions such as protein degradation, intracellular...
MCHMDA:Predicting Microbe-Disease Associations Based on Similarities and...
With the development of high-through sequencing technology and microbiology, many studies have evidenced that microbes are associated with human diseases, such as obesity...
MGRFE: Multilayer Recursive Feature Elimination Based on an Embedded Genetic...
Microarray gene expression data have become a topic of great interest for cancer classification and for further research in the field of bioinformatics. Nonetheless, due to the...
ANCA: Alignment-Based Network Construction Algorithm
Dynamic biological networks model changes in the network topology over time. However, often the topologies of these networks are not available at specific time points. Existing...
Bayesian Inference in Y-Linked Two-Sex Branching Processes with Mutations...
A Y-linked two-sex branching process with mutations and blind choice of males is a suitable model for analyzing the evolution of the number of carriers of a Y-linked allele and...
CNV IFTV: An Isolation Forest and Total Variation-Based Detection of CNVs...
Accurate detection of copy number variations from short-read sequencing data is challenging due to the uneven distribution of reads and the unbalanced amplitudes of gains and...
Vaccines: Herd Immunity, Passports, Reaching the Underserved
As the COVID-19 vaccinations roll out with increasing speed, questions are now arising about herd immunity, the need to reach underserved populations, and a proposed passport...