BioTech Mag Search: Genes
Scientists take major step toward Angelman Syndrome gene therapy
Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the...
11 hours ago - ScienceDaily
Transcription factors may inadvertently lock in DNA mistakes
Transcription factor proteins are the light switches of the human genome. By binding to DNA, they help turn genes 'on' or 'off' and start the important process of copying DNA...
13 hours ago - Phys - 2 articles
The HiFi Sequencing Advantage for Metagenome Assembly
Assembly and binning of metagenome data are the first steps in many metagenomics analysis pipelines, and with good reason. Metagenome assembled genomes and circularized MAGs...
15 hours ago - Pacific Biosciences
Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models
Genomic profiling of solid human tumors by projects such as The Cancer Genome Atlas has provided important information regarding the somatic alterations that drive cancer...
20 hours ago - BMC Bioinformatics
Biogen finally culls MS dud opicinumab, adds SMA gene therapy to the garbage heap
Biogen finally culls MS dud opicinumab, adds SMA gene therapy to the garbage heap badams Wed, 10/21/2020 - 07:23
21 hours ago - Fierce Biotech
MAL62 overexpression enhances uridine diphosphoglucose-dependent trehalose synthesis and glycerol metabolism for cryoprotection of baker's yeast in lean dough
In Saccharomyces cerevisiae, alpha-glucosidase is a key enzyme in maltose metabolism. In addition, the overexpression of the alpha-glucosidase-encoding gene MAL62 has been...
21 hours ago - Microbial Cell Factories
Novartis Gene Therapies: Supply Chain Intern
Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological...
1 day ago - San Diego Biotechnology
High throughput single-cell detection of multiplex CRISPR-edited gene modifications
CRISPR-Cas9 gene editing has transformed our ability to rapidly interrogate the functional impact of somatic mutations in human cancers. Droplet-based technology enables the...
1 day ago - Genome Biology - 2 articles
Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics
Summary Cytotoxic T lymphocyte-associated antigen-4 , the first immune checkpoint to be targeted clinically, has provided an effective treatment option for various...
1 day ago - Springer
Homologous Recombination Offers Advantages Over Transposition‐Based Systems to Generate Recombinant Baculovirus for Adeno‐Associated Viral Vector Production
Viral vectors have a great potential for gene delivery, but manufacturing at a pharmaceutical scale is a big challenge for the industry. The baculovirus‐insect cell system is...
1 day ago - Wiley - 2 articles
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
The HiFi Sequencing Advantage for Metagenome Assembly
Assembly and binning of metagenome data are the first steps in many metagenomics analysis pipelines, and with good reason. Metagenome assembled genomes and circularized MAGs...
WFH Series: Kestrel McCorkle
As we navigate this interesting time of working from home, we asked a few GreenLighter's what their tips and tricks are staying inspired and connected with co-workers. This...
Explicación sobre estudios de terapias experimentales contra la COVID-19
Según queda claro después de meses de pandemia, la COVID-19 afecta a la gente de varias maneras. Algunos pueden infectarse y no presentar síntomas , mientras otros tienen...
Toxic Cellular Ooze Linked to Biological Age, Disease and Disability
Cells in the body usually do what they're told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body's order...
Aging and Immune Decline: Destiny or Dynamic?
Aging is typically linked with the point in time when it causes problems. But there are many types of aging. There's chronological age, which we celebrate each year, sometimes...
Berkeley Lab Building Efficiency Campaign Drives $95M in Annual Energy Savings
By Natalie Pawelski One hundred and four U.S. companies, schools, governments, and institutions are taking their building energy savings to a new level with the Department of...
Chasing Their Tails but Getting Somewhere: Reimagining the Shape of Noise...
Univ. of Tennessee undergrad Elliot Perryman worked with Biosciences staff scientist Peter Zwart during his fall 2019 Berkeley Lab Undergraduate Research internship. Tenacity...
Fabrication of Biogenic Silica Nanostructures from Sorghum bicolor Leaves...
Abstract Due to the large production of sorghum, the generation of associated agricultural residues, which contain high contents of silica, is inevitable. Also, these...
A Review of US Army Research Contributing to Cognitive Enhancement in...
Abstract The US Department of Defense, including the Army, Air Force, Navy, and Defense Advanced Research Projects Agency has engaged in cognitive enhancement research and...
Designed proteinoid polymers and nanoparticles encapsulating risperidone for...
Nanoparticles incorporating drug formulations can be used to facilitate passage through biological barriers including the blood-brain barrier and increase drug delivery and...