• Purification of animal immunoglobulin G using peptoid affinity ligands

    11 days ago - By Wiley

    Abstract
    The availability of highly pure animal antibodies is critical in the production of diagnostic tools and biosensors. The peptoid PL16, previously isolated from an ensemble of peptoid variants of the IgG‐binding peptide HWRGWV, was utilized in this work as affinity ligand on WorkBeads resin for the purification of immunoglobulin G from a variety of mammalian sources and chicken immunoglobulin Y. The chromatographic protocol initially optimized for murine serum and ascites, was subsequently employed for processing rabbit, goat and sheep, donkey, llama, and chicken sera. The...
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