• Long non-coding RNA exploration for mesenchymal stem cell characterisation

    12 days ago - By Springer

    Abstract
    Background
    The development of RNA sequencing and the corresponding emergence of public datasets have created new avenues of transcriptional marker search. The long non-coding RNAs constitute an emerging class of transcripts with a potential for high tissue specificity and function. Therefore, we tested the biomarker potential of lncRNAs on Mesenchymal Stem Cells , a complex type of adult multipotent stem cells of diverse tissue origins, that is frequently used in clinics but which is lacking extensive characterization.
    Results
    We developed a dedicated bioinformatics pipeline for...
    Read more ...