• Relationship of intracellular proteolysis with CAP1 and cofilin1 in non-small-cell lung cancer

    1 month ago - By Journal of Biosciences

    Abstract
    The main cause of death in non-small-cell lung cancer is tumor progression, in which metastasis and invasion play an important role. The metastatic cascade is marked by a change in morphological, biological, biochemical and functional characteristics, including the acquisition of cellular mobility. The migration activity of tumor cells determines the work of actin-binding proteins that cause their functional partners CAP1 and cofilin. Of interest is the study of the regulation of working tandem CAP1/cofilin in NSCLC. The mechanism that regulates the level of proteins in cells is...
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