• The role and possible mechanism of the long noncoding RNA LINC01260 in nonalcoholic fatty liver disease

    6 days ago - By Springer

    Abstract
    Objective
    To investigate the differential expression profile of lncRNAs in the nonalcoholic fatty liver disease model induced by oleic acid and to further explore the role of LINC01260 in NAFLD, providing theoretical support for the clinical value of lncRNAs in NAFLD.
    Methods
    OA was used to induce steatosis in normal human LO2 hepatocytes for 48 h and was verified by Oil red O staining. Differential expression profiles of lncRNAs were obtained by eukaryotic circular sequencing techniques. A gain-of-function strategy for LINC01260 was adopted, Oil red O staining and...
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