• Identification of key genes and pathways associated with sex differences in rheumatoid arthritis based on bioinformatics analysis

    6 days ago - By Springer

    Abstract
    Introduction
    Women are more likely than men to develop the chronic, progressive autoimmune disease known as rheumatoid arthritis. Although there may be a complex interplay between sex-based differences and autoimmune dysfunction. Their function in RA is largely unknown, though. The purpose of this study was to pinpoint the crucial genes and metabolic pathways that control biological variations in RA between men and women.
    Methods
    First, the Gene Expression Omnibus database's gene expression information for GSE39340 and GSE55457 was downloaded. R software was used to find each of...
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