BioTech Mag Search: Bioinformatics
TCF3 Induces DNMT1 Expression to Regulate Wnt Signaling Pathway in Glioma
13 days ago - By Springer
Abstract
The epigenetic alteration is widely understood as the key to cancer initiation. Herein, we intended to clarify the role of transcription factor 3 in the development of glioma and the behind epigenetic mechanism. Through bioinformatics analysis, we identified a TCF3-DNA methyltransferase 1 -secreted frizzled related protein 1 axis which was differentially expressed and interacted in gliomas. More specifically, TCF3 activated DNMT1 transcription, and DNMT1 repressed SFRP1 expression. TCF3 and DNMT1 were overexpressed, while SFRP1 was downregulated in glioma. Functionally, TCF3...
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Genetic roots of 3 mitochondrial diseases ID'd via new approach
Researchers have identified the genetic causes of three mitochondrial diseases by figuring out what dozens of poorly understood mitochondrial proteins do. The functions of...
Novel environmental DNA monitoring method for identifying rare and...
Researchers have outlined a powerful new tool for monitoring trade of rare and endangered fish species in Hong Kong wet markets. Using environmental DNA present in the drain...
Scientist, Digital Pathology R&D - Novartis - Carlsbad, CA
Navigate Biopharma, a fully owned subsidiary of Novartis, provides assay development, clinical trial testing, and companion diagnostics services to companies...
BEXCIS: Bayesian methods for estimating the degree of the skewness of X...
X chromosome inactivation is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has...
Gene co-expression network based on part mutual information for gene-to-gene...
Finding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly use non-direct associations, such as...
How mice choose the best escape route
Escaping imminent danger is essential for survival. Animals must learn a new environment fast enough for them to be able to choose the shortest route to safety. But how do they...
NVG- Immuno-Oncology Flow Cytometry Analysis Expert -585 - NewAge Clinical...
E. Must have at least 5 years of experience in analysis of high dimensional flow cytometry data, specifically...
Modeling and equilibrium studies on the recovery of praseodymium...
In this research, the possibility of using hydrogenated Dowex 50WX8 resin for the recovery and separation of Pr, Dy and Y from aqueous nitrate solutions were carried out. Dowex...
Robust network topologies for temperature-inducible bioswitches
Thermoinducible bioswitches are unique in that the all-or-none switch response is triggered by temperature, which is a global factor that impacts all biochemical reaction...
Issue Information
Plant Biotechnology Journal, Volume 20, Issue 6, Page 1007-1008, June 2022.