• Potential ferroptosis-related diagnostic and prognostic biomarkers in laryngeal cancer

    2 monthes ago - By Springer

    Abstract
    Purpose
    Laryngeal cancer is a common malignant tumor of the head and neck. However, the relationship between ferroptosis and LC is still unclear. The aim of this study was to identify potential ferroptosis-related biomarkers for diagnosis and prognosis in LC.
    Methods
    We screened differentially expressed genes related to ferroptosis in LC from the TCGA and FerrDb database. DEGs were identified and enrichment by GO/KEGG, GSEA, GSVA analysis. PPI analysis was performed using String and Cytoscape, then hub genes were extracted. Furthermore, ROC analysis, pan-cancer analysis, gene...
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