• Silencing of Long Non-coding RNA TTN-AS1 Inhibits Hepatocellular Carcinoma Progression by the MicroRNA-134/ITGB1 Axis

    11 days ago - By Springer

    Abstract
    Background
    Hepatocellular carcinoma causes considerable mortality worldwide. Long non-coding RNA TTN-AS1 has been recently identified as an oncogene in several cancers, but its role in HCC and the molecules remain largely unknown.
    Aims
    The study aims to probe the function of lncRNA TTN-AS1 in HCC progression and the molecules involved.
    Methods
    Differentially expressed lncRNAs between HCC and the adjacent normal tissues were analyzed using a microarray. TTN-AS1 expression in HCC and normal tissues and cells was determined. Targeting relationships between TTN-AS1 and miR-134 and...
    Read more ...