• Establishment of a novel myocarditis mouse model based on cyclosporine A

    13 days ago - By Springer

    Abstract
    Background
    Myocarditis is a myocardial injury that can easily cause adolescent death. Traditional research models of animal invasion with viral components, lipopolysaccharide or porcine myocardial myosin, among others, have the shortcomings of potential biological safety hazards and high animal mortality.
    Objective
    To explore the construction of a novel myocarditis model with cyclosporine A and the potential genes and pathways associated with it.
    Methods
    BALB/c mice were used in this study, and cyclosporin A and LPS were injected into the peritoneal cavity of mice. The successful...
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