• MicroRNA-199a-3p Exhibits Beneficial Effects in Asymptomatic Atherosclerosis by Inhibiting Vascular Smooth Muscle Cell Proliferation and Migration

    10 days ago - By Springer

    Abstract
    Atherosclerosis is a serious healthy burden worldwide, it occurs accompany with the disfunction of vascular smooth muscle cells. MicroRNAs play pivotal role in the pathogenesis of various diseases. This study aimed to investigate the expression and clinical value of miR-199a-3p in patients with asymptomatic AS, and further explore its regulatory role on VSMCs biological function. Quantitative real-time PCR was used to estimate the expression of miR-199a-3p. Correlation of miR-199a-3p with carotid intima-media thickness and C-reactive protein was evaluated by Pearson correlation...
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