• Computational drug repurposing study of the RNA binding domain of SARS‐CoV‐2 nucleocapsid protein with antiviral agents

    8 days ago - By Wiley

    Abstract
    The recent outbreak of coronavirus disease in China caused by the severe acute respiratory syndrome coronavirus 2 has led to worldwide human infections and deaths. The nucleocapsid protein of coronaviruses is a multifunctional RNA binding protein necessary for viral RNA replication and transcription. Therefore, it is a potential antiviral drug target, serving multiple critical functions during the viral life cycle. This study addresses the potential to repurpose antiviral compounds approved or in development for treating human CoV induced infections against SARS‐CoV‐2 N. For this...
    Read more ...