• Peroxisome compartmentalization of a toxic enzyme improves alkaloid production

    9 days ago - By ACS Division of Biological Chemistry

    Nature Chemical Biology, Published online: 12 October 2020; doi:10.1038/s41589-020-00668-4 Increased production of -reticuline and other alkaloids is achieved through alleviating norcoclaurine synthase toxicity by targeting the enzyme to the peroxisome plus enlarging peroxisomes by expression of engineered transcription factors.
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