• SoluProt: Prediction of Soluble Protein Expression in Escherichia coli

    13 days ago - By Oxford Journals

    AbstractMotivationPoor protein solubility hinders the production of many therapeutic and industrially useful proteins. Experimental efforts to increase solubility are plagued by low success rates and often reduce biological activity. Computational prediction of protein expressibility and solubility in Escherichia coli using only sequence information could reduce the cost of experimental studies by enabling prioritisation of highly soluble proteins.ResultsA new tool for sequence-based prediction of soluble protein expression in Escherichia coli, SoluProt, was created using the gradient...
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  • Novel ethanol production using biomass preprocessing to increase ethanol yield and reduce overall costs

    13 days ago - By Biotechnology for Biofuels

    Ethanol biorefineries need to lower their overall production costs to become economically feasible. Two strategies to achieve this are to reduce costs using cheaper feedstocks or to increase the ethanol produc...
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