• SNHG1/miR-194-5p/MTFR1 Axis Promotes TGFβ1-Induced EMT, Migration and Invasion of Tongue Squamous Cell Carcinoma Cells

    10 days ago - By Springer

    Abstract
    Tongue squamous cell carcinoma is a common malignancy with aggressive biological behaviors. Mitochondrial fission regulator 1 , is aberrantly expressed in head and neck squamous cell carcinoma , but its role in TSCC remains unclear. We aimed to explore the role of MTFR1 in TSCC. The expression of long non-coding RNA small nucleolar RNA host gene 1 , microRNA-194-5p and MTFR1 in TSCC cells was measured by RT-qPCR. Luciferase reporter assay and RNA pull down assay were applied to confirm the binding capacity between miR-194-5p and SNHG1. TSCC cell invasion and migration were...
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