• Characterization of Glucose‐Binding Proteins Isolated from Health Volunteers and Human Type 2 Diabetes Mellitus Patients

    2 monthes ago - By Wiley

    Abstract
    Background
    Glucose is one of the most important monosaccharides. Although hyperglycemia in T2DM lead to a series of changes, however, little is known about the alterations of serum proteins in T2DM, especially those proteins with glucose affinity.
    Methods
    In this study, the GlcBPs of serum were isolated from 30 HV and 30 T2DM patients by GMPC and identified by mass spectrum analysis. GO enrichment analysis and KEGG indicated the main gene annotations and pathways of this GlcBPs, while Motif-X webtool provided the potential glucose-binding domains. Further docking analysis and...
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