• Identification S100A9 as a potential biomarker in neuroblastoma

    1 month ago - By Springer

    More than half of Neuroblastoma patients presented with distant metastases and the relapse of metastatic patients was up to 90%. It is urgent to explore a biomarker that could facilitate the prediction of metastasis in NB patients.
    Methods and results
    In the present study, we systematically analyzed Gene Expression Omnibus datasets and focused on identifying the critical molecular networks and novel key hub genes implicated in NB metastasis. In total, 176 up-regulated and 19 down-regulated differentially expressed genes were identified. Based on these DEGs, a PPI...
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