• HAPPI GWAS: Holistic Analysis with Pre- and Post-Integration GWAS

    19 days ago - By Oxford Journals

    AbstractMotivationAdvanced publicly available sequencing data from large populations have enabled informative genome-wide association studies that associate SNPs with phenotypic traits of interest. Many publicly available tools able to perform GWAS have been developed in response to increased demand. However, these tools lack a comprehensive pipeline that includes both pre-GWAS analysis, such as outlier removal, data transformation and calculation of Best Linear Unbiased Predictions or Best Linear Unbiased Estimates. In addition, post-GWAS analysis, such as haploblock analysis and...
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