• Neighbourhoods in the Yeast Regulatory Network in Different Physiological States

    1 month ago - By Oxford Journals

    AbstractMotivationThe gene expression regulatory network in yeast controls the selective implementation of the information contained in the genome sequence. We seek to understand how, in different physiological states, the network reconfigures itself to produce a different proteome.ResultsThis article analyses this reconfiguration, focusing on changes in the local structure of the network. In particular, we define, extract and compare the 1-neighbourhoods of each transcription factor, where a 1-neighbourhood of a node in a network is the minimal subgraph of the network containing all nodes...
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