• SCEPTRE improves calibration and sensitivity in single-cell CRISPR screen analysis

    1 month ago - By Genome Biology

    Single-cell CRISPR screens are a promising biotechnology for mapping regulatory elements to target genes at genome-wide scale. However, technical factors like sequencing depth impact not only expression measur...
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  • An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes

    1 month ago - By Genome Biology

    We have developed an efficient and inexpensive pipeline for streamlining large-scale collection and genome sequencing of bacterial isolates. Evaluation of this method involved a worldwide research collaboratio...
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