BioTech Mag Search: Genomics
Emergence of networks of shared restriction-modification systems in phage-bacteria ecosystems
9 monthes ago - By Journal of Biosciences
Abstract
Restriction-modification systems are the most ubiquitous bacterial defence systems against bacteriophages. Using genome sequence data, we showed that RM systems are often shared among bacterial strains in a structured way. Examining the network of interconnections between bacterial strains within genera, we found that many strains share more RM systems than expected compared with a suitable null model. We also found that many genera have a larger than expected number of bacterial strains with unique RM systems. We used population dynamics models of closed and open phage-bacteria...
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