• Genetic impacts on DNA methylation: research findings and future perspectives

    9 days ago - By Genome Biology

    Multiple recent studies highlight that genetic variants can have strong impacts on a significant proportion of the human DNA methylome. Methylation quantitative trait loci, or meQTLs, allow for the exploration...
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  • MARS: leveraging allelic heterogeneity to increase power of association testing

    9 days ago - By Genome Biology

    In standard genome-wide association studies , the standard association test is underpowered to detect associations between loci with multiple causal variants with small effect sizes. We propose a statist...
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  • Genome-wide variant-based study of genetic effects with the largest neuroanatomic coverage

    9 days ago - By BMC Bioinformatics

    Brain image genetics provides enormous opportunities for examining the effects of genetic variations on the brain. Many studies have shown that the structure, function, and abnormality (e.g., those related to ...
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