• Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections

    1 month ago - By Springer

    Abstract
    Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to control microbial infections. Although nucleic acid testing is widely deployed for the detection of antibiotic resistant bacteria, the current techniques-mainly based on polymerase chain reaction -are time-consuming and laborious. There is an urgent need to develop new strategies to control bacterial infections and the spread of antimicrobial resistance. The CRISPR-Cas system is an adaptive immune system found in many prokaryotes that presents attractive opportunities to target and edit...
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