• Knowledge extraction from literature and enzyme sequences complements FBA analysis in metabolic engineering

    25 days ago - By Wiley

    Graphical Abstract and Lay Summary
    Flux balance analysis is a useful method for improving the bio-production of target compounds. However, it is often difficult to accurately predict metabolic manipulation strategies using FBA alone. Thus, in this study, we proposed a method using literature search and enzyme search to mutually complement the FBA-based metabolic manipulation strategies. As a result, this method is useful for searching and presenting more effective metabolic manipulation strategies.
    Abstract
    Flux balance analysis using genome-scale metabolic model is a useful method for...
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  • Metabolic engineering of Deinococcus radiodurans for pinene production from glycerol

    Metabolic engineering of Deinococcus radiodurans for pinene production from glycerol

    25 days ago - By Microbial Cell Factories

    The objective of this work was to engineer Deinococcus radiodurans R1 as a microbial cell factory for the production of pinene, a monoterpene molecule prominently used for the production of fragrances, pharmaceut...
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