• Integration of Ion Exchange Resin Materials for a Downstream‐Processing Approach of an Imine Reductase ‐Catalyzed Reaction

    2 monthes ago - By Wiley

    Abstract
    In this study an ion exchange resin‐based downstream‐processing concept for imine reductase ‐catalyzed reactions was investigated. As a model reaction, 2‐methylpyrroline was converted to its corresponding product ‐2‐methylpyrrolodine with > 99% of conversion by the ‐selective IRED from Paenibacillus elgii B69. Under optimized reaction conditions full conversion was achieved using a substrate concentration of 150 mmol·L −1 and 500 mmol·L −1 of d ‐glucose. Seven commercially available cation and anion exchange resins were studied with respect to their ability to recover the product...
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