• DNAModAnnot: a R toolbox for DNA modification filtering and annotation

    1 month ago - By Oxford Journals

    AbstractMotivationLong-read sequencing technologies can be employed to detect and map DNA modifications at the nucleotide resolution on a genome-wide scale. However, published software packages neglect the integration of genomic annotation and comprehensive filtering when analyzing patterns of modified bases detected using Pacific Biosciences or Oxford Nanopore Technologies data. Here, we present DNAModAnnot, a R package designed for the global analysis of DNA modification patterns using adapted filtering and visualization tools.ResultsWe tested our package using PacBio sequencing data to...
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