• A survey of human histone H1 subtypes interaction networks: implications for histones H1 functioning

    1 month ago - By Wiley

    Abstract
    To show a spectrum of histone H1 subtypes activity realized through the protein‐protein interactions, data selected from APID resources were processed with sequence‐based bioinformatics approaches. Histone H1 subtypes participate in over half a thousand interactions with nuclear and cytosolic proteins engaged in the enzymatic activity and binding of nucleic acids and proteins. Small scale networks of H1 subtypes have similar topological parameters which are, however, different for networks hubs between subtype H1.1 and H1.4 and subtype H1.3 and H1.5 (P 
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