• Circ-WDR27 regulates mycobacterial vitality and secretion of inflammatory cytokines in Mycobacterium tuberculosis-infected macrophages via the miR-370-3p/FSTL1 signal network

    15 days ago - By Journal of Biosciences

    Abstract
    Tuberculosis is a common disease caused by Mycobacterium tuberculosis infection. Our study was to explore the function and mechanism of circular RNA WD repeat domain 27 in TB progression. Cell viability and apoptosis were detected by 3--2, 5-diphenyl tetrazolium bromide assay and flow cytometry. Protein quantification was performed by Western blot. Inflammatory cytokines were examined using enzyme-linked immunosorbent assay. RNA levels were assayed via quantitative reverse-transcription polymerase chain reaction. M.tb survival was assessed using colony-forming unit assay. Target...
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