• Design of Multiepitope Vaccine Construct Against Non-typhoidal Salmonellosis and its Characterization Using Immunoinformatics Approach

    1 month ago - By Springer

    Abstract
    Non-typhoidal salmonellosis is a food-borne zoonotic disease of human and veterinary importance. Besides enteric infections, most often it leads to invasive systemic bacteremia in immunocompromised patients leading to mortality. Emergence of antimicrobial-resistant species warrant the development of newer preventive approaches against NTS. Here, we adopted an in-silico approach to design a multiepitope-based peptide vaccine which will likely enhance the body's immune response against most commonly isolated serovars ( Salmonella Typhimurium, Salmonella Enteritidis and Salmonella...
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  • Lessons Learned from Cutting-Edge Immunoinformatics on Next-Generation COVID-19 Vaccine Research

    1 month ago - By Springer

    Abstract
    Presently, immunoinformatics and bioinformatics approaches are contributing actively to COVID-19 vaccine research. The first immunoinformatics-based vaccine construct against SARS-CoV-2 was published in February 2020. Following this, immunoinformatics and bioinformatics approaches have created a new direction in COVID-19 vaccine research. Several researchers have designed the next-generation COVID-19 vaccines using these approaches. Presently, immunoinformatics has accelerated immunology research immensely in the area of COVID-19. Hence, we have tried to depict the current...
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