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An Analytical Review of Computational Drug Repurposing
5 days ago - By IEEE/ACM
Drug repurposing is a vital function in pharmaceutical fields and has gained popularity in recent years in both the pharmaceutical industry and research community. It refers to the process of discovering new uses and indications for existing or failed drugs. It is cost-effective and reliable in contrast to experimental drug discovery, which is a costly, time-consuming, and risky process and limited to a relatively small number of targets. Accordingly, a plethora of computational methodologies have been propounded to repurpose drugs on a large scale by utilizing available high throughput...
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
UFGI Publication Round-up: Week of 4/12/21
Virtual special issue of the fifth biennial meeting of the north american society for comparative endocrinology (Sociedad norteamericana de endocrinologĂa comparada; SocietĂ©...
Comparative regulomics supports pervasive selection on gene dosage following...
Whole genome duplication events have played a major role in eukaryotic genome evolution, but the consequence of these extreme events in adaptive genome evolution is still not...
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via...
Although using a blockade of programmed death-ligand 1 to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy...
Unlocking richer intracellular recordings
A forward-thinking group of researchers has identified a flexible, low-cost, and biocompatible platform for enabling richer intracellular recordings.
U.S. Power Sector is Halfway to Zero Carbon Emissions
By Kiran Julin and Bentham Paulos Concerns about climate change are driving a growing number of states, utilities, and corporations to set the goal of zeroing out power-sector...
Aging signatures across diverse tissue cells in mice
Researchers have identified molecular signatures of the aging process in mice.
Amoeba biology reveals potential treatment target for lung disease
In a series of experiments that began with amoebas - single-celled organisms that extend podlike appendages to move around - scientists say they have identified a genetic...
Molecular assembly line to design, test drug compounds streamlined
Researchers have fine-tuned the molecular assembly line that creates antibiotics via engineered biosynthesis.
Simple genetic modification aims to stop mosquitoes spreading malaria
Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria.
Novel guidelines help select optimal deconvolution method
Biomedical scientists are increasingly using deconvolution methods, those used to computationally analyze the composition of complex mixtures of cells. One of their challenges...