• Cancer-linked mutation accelerates growth of abnormal stroke-causing brain blood vessels

    9 days ago - By ScienceDaily

    Researchers have discovered an explanation for why cerebral cavernous malformations - clusters of dilated blood vessels in the brain - can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene could exacerbate existing CCMs in the brain. Furthermore, repurposing an already existing anticancer drug showed promise in mouse models of CCMs in improving brain-vascular health and preventing bleeding into the brain tissue.
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