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Interaction of leachable model compounds and their impact on Chinese hamster ovary cell cultivation
7 days ago - By Wiley
Abstract
The presence of leachables in biopharmaceutical processes using single‐use technologies is well known. For the detection and quantification of the latter, extractable studies of SUT are very common nowadays. Although a mixture of compounds is regularly found in extractable studies, research has only been carried out regarding the effect of individual compounds on cell culture and the cumulative effect of a mix of leachables has not been investigated yet. In this study, a set of leachable model compounds was chosen and the effect of the LMCs on a Chinese hamster ovary DG44 cell...
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2nd International Conference on Generic Drugs and Biosimilars
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
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