• Cellinker: a platform of ligand-receptor interactions for intercellular communication analysis

    1 month ago - By Oxford Journals

    AbstractMotivationLigand-receptor interactions mediate cell adhesion, recognition and communication and play essential roles in physiological and pathological signaling. With the rapid development of single-cell RNA sequencing technologies, systematically decoding the intercellular communication network involving L-R interactions has become a focus of research. Therefore, construction of a comprehensive, high-confidence and well-organized resource to retrieve L-R interactions in order to study the functional effects of cell-cell communications would be of great value.ResultsIn this study...
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