• Differential expression of miRNA in histological subtype of Wilms tumor

    10 days ago - By Springer

    Abstract
    Introduction
    Wilms tumor is the most common renal malignancy in children and difficult to differentiate from other paediatric abdominal tumors radiologically, necessitating an invasive procedure for diagnosis. Previous studies have shown the potential role of miRNA as biomarkers for diagnosis, histological subtyping and prognosis. In this study, we are exploring the role of miRNA in the histological subtyping of Wilms tumor in the Indian population.
    Materials and methods
    A total of 15 cases of Wilms tumor were evaluated for global miRNA expression analysis by microarray. Total RNA...
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