• Modeling and cleaning RNA-seq data significantly improve detection of differentially expressed genes

    18 days ago - By BMC Bioinformatics

    RNA-seq has become a standard technology to quantify mRNA. The measured values usually vary by several orders of magnitude, and while the detection of differences at high values is statistically well grounded,...
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  • LmerSeq: an R package for analyzing transformed RNA-Seq data with linear mixed effects models

    18 days ago - By BMC Bioinformatics

    Studies that utilize RNA Sequencing in conjunction with designs that introduce dependence between observations require specialized analysis tools to accommodate this addi...
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