• Cre-Controlled CRISPR: Conditional gene inactivation just got easier

    9 days ago - By Phys

    The ability to turn a gene off only in a specific cell type is essential to modern life science. Thanks to the Cre-Controlled CRISPR it has just became simpler. The new method developed by researchers from the Center for Regenerative Therapies Dresden at TU Dresden with support from the DRESDEN-concept Genome Center offers a fast and easy approach for conditional gene inactivation. The findings were published in the journal Nature Communications.
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  • ScSorter: assigning cells to known cell types according to marker genes

    9 days ago - By Genome Biology

    On single-cell RNA-sequencing data, we consider the problem of assigning cells to known cell types, assuming that the identities of cell-type-specific marker genes are given but their exact expression levels a...
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