• ScTPA: A web tool for single-cell transcriptome analysis of pathway activation signatures

    2 monthes ago - By Oxford Journals

    AbstractMotivationAt present, a fundamental challenge in single-cell RNA-sequencing data analysis is functional interpretation and annotation of cell clusters. Biological pathways in distinct cell types have different activation patterns, which facilitates the understanding of cell functions using single-cell transcriptomics. However, no effective web tool has been implemented for single-cell transcriptome data analysis based on prior biological pathway knowledge.ResultsHere, we present scTPA, a web-based platform for pathway-based analysis of single-cell RNA-seq data in human and mouse...
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