• Spathial: an R package for the evolutionary analysis of biological data

    4 days ago - By Oxford Journals

    AbstractSummaryA primary problem in high-throughput genomics experiments is finding the most important genes involved in biological processes. In this applications note, we introduce spathial, an R package for navigating high-dimensional data spaces. spathial implements the Principal Path algorithm, which is a topological method for locally navigating on the data manifold. The package, together with the core algorithm, provides several high-level functions for interpreting the results. One of the analyses we propose is the extraction of the genes that are mainly involved in the progress...
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