BioTech Mag Search: Stem Cell
Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation
12 days ago - By Phys
The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide. Targeting endocrine dysfunction at an early stage by stimulating the formation of specific enteroendocrine cells from intestinal stem cells could be a promising regenerative approach for diabetes therapy. For this, however, a detailed understanding of the intestinal stem cell lineage hierarchy and the signals regulating the recruitment of the different...
Read more ...Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation
12 days ago - By ScienceDaily
The gut plays a central role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide. Targeting endocrine dysfunction by stimulating the formation of specific enteroendocrine cells from intestinal stem cells could be a promising regenerative approach for diabetes therapy. For this, a detailed understanding of the intestinal stem cell lineage and the signals regulating the recruitment of intestinal cell types is critical.
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
The Importance of Good Documentation Practices
Written By: Akshaya Mohan, Regulatory Affairs Manager, PSC Biotech® Documentation is a “record” or “evidence” of an event that has happened. In the life-science industry “If it...
Bond LSC Alumnus Celebrates Black Botanists Through Social Media Initiative
Morgan Halane, Bond Life Sciences Center alumnus, visits his former middle school to get students interested in botany. | photo contributed by Morgan Halane, Bond LSC. By...
Long-read transcriptome sequencing reveals abundant promoter diversity in...
Deregulated gene expression is a hallmark of cancer; however, most studies to date have analyzed short-read RNA sequencing data with inherent limitations. Here, we combine...
MicroExonator enables systematic discovery and quantification of microexons...
Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and...
Tidybulk: an R tidy framework for modular transcriptomic data analysis
Recently, efforts have been made toward the harmonization of transcriptomic data structures and workflows using the concept of data tidiness, to facilitate modularisation. We...
Estimating the accuracy of pharmacophore‐based detection of cognate...
Abstract Secreted and membrane‐bound members of the immunoglobulin superfamily encompass a large, diverse array of proteins that play central roles in immune response and...
Improvement of host‐induced gene silencing efficiency via...
Summary Host‐induced gene silencing emerged as a new strategy for pest control. However, RNAi efficiency is reported to be low in Lepidoptera, which are composed of many...
Green giant - a tiny chloroplast genome with mighty power to produce...
Summary Free‐living cyanobacteria were entrapped by eukaryotic cells ~2 billion years ago, ultimately giving rise to chloroplasts. After a century of debate, the presence of...
European eels - one gene pool fits all
European eels spawn in the subtropical Sargasso Sea but spend most of their adult life in a range of fresh- and brackish waters, across Europe and Northern Africa. Using...
Spontaneous cell fusions amplify genetic diversity within tumors
Scientists generally believe that cancers lack a powerful and important diversification mechanism available to pathogenic microbes - the ability to exchange and recombine...