• Identification of a repurposed drug as an inhibitor of Spike protein of human coronavirus SARS-CoV-2 by computational methods

    12 days ago - By Journal of Biosciences

    Abstract
    Severe acute respiratory syndrome coronavirus is an emerging new viral pathogen that causes severe respiratory disease. SARS-CoV-2 is responsible for the outbreak of COVID-19 pandemic worldwide. As there are no confirmed antiviral drugs or vaccines currently available for the treatment of COVID-19, discovering potent inhibitors or vaccines are urgently required for the benefit of humanity. The glycosylated Spike protein directly interacts with human angiotensin-converting enzyme 2 receptor through the receptor-binding domain of S-protein. As the S-protein is exposed to the surface...
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