• Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

    14 days ago - By Genome Biology

    Population structure among study subjects may confound genetic association studies, and lack of proper correction can lead to spurious findings. The Genotype-Tissue Expression project largely contains i...
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  • Sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression

    14 days ago - By Genome Biology

    Genetic regulation of gene expression, revealed by expression quantitative trait loci , exhibits complex patterns of tissue-specific effects. Characterization of these patterns may allow us to better un...
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