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By Wiley - Oct 20, 2021
DEFINITIVE SCREENING ACCELERATES TAXOL BIOSYNTHETIC PATHWAY OPTIMIZATION AND SCALE UP IN SACCHAROMYCES CEREVISIAE CELL FACTORIES
Abstract Background Recent technological advancements in synthetic and systems biology have enabled the construction of microbial cell...
Drugs, Biological, Biology, Drug, Systems biology, Engineering, Biologic, Industrial, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
IMPROVEMENT OF THE PERFORMANCE OF ANTICANCER PEPTIDES USING A DRUG REPOSITIONING PIPELINE
Abstract The use of anticancer peptides as an alternative/complementary strategy to conventional chemotherapy treatments has been shown...
Drug, Drugs, Cancer, Genes, Gene, Research Article -
By Wiley - Oct 20, 2021
STRUCTURES AND INTERACTIONS OF INSULIN‐LIKE PEPTIDES FROM CONE SNAIL VENOM
Abstract The venomous insulin-like peptides released by certain cone snails stimulate hypoglycemic shock to immobilize fish and catch...
Biologic, Biology, Biological, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
CONFORMATIONAL VARIABILITY OF LOOPS IN THE SARS‐COV‐2 SPIKE PROTEIN
Abstract The SARS-CoV-2 spike protein facilitates viral infection, and has been the focus of many structure determination efforts....
Protein, Applied, Paper, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
STRUCTURE AND DYNAMICS OF THE SOMATOSTATIN RECEPTOR 3 ‐LIGAND BINDING IN PRESENCE OF LIPIDS EXAMINED USING COMPUTATIONAL STRUCTURAL BIOLOGY METHODS
Abstract In the past two decades, the structural biology studies on G-protein coupled receptors are on the rise. Understanding the...
Computers, Biology, Biological, Biologic, Cellular, Protein, Structural biology, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
STRUCTURAL AND BIOCHEMICAL STUDIES OF AN ITERATIVE RIBOSOMAL PEPTIDE MACROCYCLASE
Abstract Microviridins, tricyclic peptide natural products originally isolated from cyanobacteria, function as inhibitors of diverse...
Chemistry, Biochemical, Biosynthesis, Nature, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
CELLULOSE SYNTHASE‐LIKE PROTEIN OSCSLD4 PLAYS AN IMPORTANT ROLE IN THE RESPONSE OF RICE TO SALT STRESS BY MEDIATING ABA BIOSYNTHESIS TO REGULATE OSMOTIC STRESS TOLERANCE
Summary Cell wall polysaccharide biosynthesis enzymes play important roles in plant growth, development, and stress responses. The...
Enzymes, Genes, Biosynthesis, Plants, Environmental, Protein, Gene, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
GENOMIC SIGNATURES OF DOMESTICATION AND ADAPTATION DURING GEOGRAPHICAL EXPANSIONS OF RICE CULTIVATION
Abstract Rice , a global staple food now grown on all inhabited continents, was domesticated from its wild progenitor, O. rufipogon...
Environment, Food, Asia, Genome, Genomics, BRIEF COMMUNICATIONS -
By Wiley - Oct 20, 2021
ISSUE INFORMATION
Biotechnology Progress, Volume 37, Issue 5, September/October 2021.
BioTechnology, ISSUE INFORMATION -
By Wiley - Oct 20, 2021
PLASTIDIC PYRUVATE DEHYDROGENASE COMPLEX E1 COMPONENT SUBUNIT ALPHA1 IS INVOLVED IN GALACTOLIPID BIOSYNTHESIS REQUIRED FOR AMYLOPLAST DEVELOPMENT IN RICE
Summary Starch accounts for over 80% of the total dry weight in cereal endosperm and determines the kernel texture and nutritional...
Enzymes, Tissue, Biosynthesis, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
THINOPYRUM INTERMEDIUM TIAP1 INTERACTS WITH A CHITIN DEACETYLASE FROM BLUMERIA GRAMINIS F. SP. TRITICI AND INCREASES THE RESISTANCE TO BGT IN WHEAT
Summary The biotrophic fungal pathogen Blumeria graminis f. sp. tritici is a crucial factor causing reduction of global wheat production....
Biosynthesis, Genes, Gene, Protein, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
COMPREHENSIVE SPEED BREEDING: A HIGH‐THROUGHPUT AND RAPID GENERATION SYSTEM FOR LONG‐DAY CROPS
Abstract Breeding cycle time largely determines the efficiency of crop genetic improvement. To accelerate the generation progress,...
Genes, AIDS, Plants, Gene, Genetics, BRIEF COMMUNICATION -
By Wiley - Oct 20, 2021
PLANT SINGLE CELL TRANSCRIPTOME HUB : AN INTEGRATED ONLINE TOOL TO EXPLORE THE PLANT SINGLE‐CELL TRANSCRIPTOME LANDSCAPE
Abstract As the basic building blocks of all living species, cells play a crucial role in sustaining life activities. Traditional bulk...
Biological, Genes, Biology, Plants, Genomics, Gene, Biologic, Research, Genome, Tissue, BRIEF COMMUNICATION -
By Wiley - Oct 20, 2021
MODULARITY‐BASED PARALLEL PROTEIN DESIGN ALGORITHM WITH AN IMPLEMENTATION USING SHARED MEMORY PROGRAMMING
Abstract Given a target protein structure, the prime objective of protein design is to find amino acid sequences that will fold/acquire...
Protein, RESEARCH ARTICLE -
By Wiley
- Oct 20, 2021
ADVANCES IN PROMOTER ENGINEERING: NOVEL APPLICATIONS AND PREDEFINED TRANSCRIPTIONAL CONTROL
Graphical Abstract and Lay Summary Promoter engineering encompasses the development of new promoters that exhibit properties that don't...
Therapeutics, Biological, Biology, Metabolic engineering, Applied, Engineering, Cellular, Biologic, REVIEW -
By Wiley - Oct 20, 2021
TMEM106B IN HUMANS AND VAC7 AND TAG1 IN YEAST ARE PREDICTED TO BE LIPID TRANSFER PROTEINS
Abstract TMEM106B is an integral membrane protein of late endosomes and lysosomes involved in neuronal function, its overexpression...
Protein, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
ALLOSTERIC REGULATION WITHIN THE HIGHLY INTERCONNECTED STRUCTURAL SCAFFOLD OF ARAC/XYLS HOMOLOGS TOLERATES A WIDE RANGE OF AMINO ACID CHANGES
Abstract To create bacterial transcription “circuits” for biotechnology, one approach is to recombine natural transcription factors,...
Protein, DNA, Engineering, Nature, BioTechnology, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
PROTEIN TERTIARY STRUCTURE PREDICTION AND REFINEMENT USING DEEP LEARNING AND ROSETTA IN CASP14
Abstract The trRosetta structure prediction method employs deep learning to generate predicted residue-residue distance and orientation...
Protein, Computers, RESEARCH ARTICLE -
By Wiley - Oct 20, 2021
CONTINUOUS AUTOMATED MODEL EVALUATION -PERSPECTIVES ON THE FUTURE OF FULLY AUTOMATED EVALUATION OF STRUCTURE PREDICTION METHODS
Abstract The Continuous Automated Model EvaluatiOn platform complements the biennial CASP experiment by conducting fully automated...
Protein, Nucleic Acids, Research, RESEARCH ARTICLE
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The headlines of BioTech Mag
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
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Connect Biopharma to Participate at the Jefferies Virtual China Biotech Summit
SAN DIEGO, CA and TAICANG, SUZHOU, China, Oct. 19, 2021 - Connect Biopharma Holdings Limited , a global clinical-stage biopharmaceutical company dedicated to improving the...
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Science Magazine: How to vaccinate the world
GreenLight Biosciences is recognised in Science Magazine for having a blueprint to vaccinate the world. Credit: Science Magazine/STEPHAN SCHMITZ/FOLIOART GreenLight Biosciences...
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GreenLight Biosciences Science Day updates investors on progress across...
7 agricultural products in development with an addressable market of $6bn that we plan to launch by 2026. Control of fungal pathogens using double-stranded RNA has been...
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UC adopts recommendations for the responsible use of Artificial Intelligence
Camille Nebeker, Ed.D., associate professor at the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego, was a member of the University of...
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Scientist - Strain Engineer - CB Therapeutics - Carlsbad, CA
CB Therapeutics is a biotech focused on the research and development of environmentally-friendly products to improve mental health, increase healthspan, and... $70,000 a...
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New Technique Paves the Way for Perfect Perovskites
Credit: iStock/Thinnapob A n exciting new solar material called organic-inorganic halide perovskites could one day help the U.S. achieve its solar ambitions and decarbonize the...
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Scientists develop new sensor to capture calcium activity in cells
A team of researchers at Georgia State University has developed a novel approach for detecting the activity of calcium within cells. The study, led by Regents' Professor of...
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Treated jute bags boost grain storage and other green goals
Taking inspiration from water repellent surfaces in nature, KAUST researchers have pioneered a simple surface treatment for traditional jute storage bags that prevents...
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OsnR is an autoregulatory negative transcription factor controlling...
Corynebacterium glutamicum is used in the industrial production of amino acids and nucleotides. During the course of fermentation, C. glutamicum cells face various stresses and...
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A synthetic promoter system for well-controlled protein expression with...
Saccharomyces cerevisiae is an important synthetic biology chassis for microbial production of valuable molecules. Promoter engineering has been frequently applied to generate...