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By Wiley - Jan 26, 2023
ENHANCING RECOMBINANT PROTEIN AND VIRAL VECTOR PRODUCTION IN MAMMALIAN CELLS BY TARGETING THE YTHDF READERS OF N6-METHYLADENOSINE IN MRNA
Abstract N 6 -methyl adenosine is the most abundant internal modification on eukaryotic mRNA and has been implicated in a wide range...
Protein, Gene, Transgenic, Cellular, Genes, RNA, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
HUMAN ADIPOSE MESENCHYMAL STROMAL CELLS GROWING INTO PCL‐NHA ELECTROSPUN SCAFFOLDS UNDERGO HYPOXIA ADAPTIVE ULTRASTRUCTURAL CHANGES
Abstract Human Adipose-Derived Mesenchymal Stem/Stromal Cells have great potential for tissue regeneration. Since transplanted hAD-MSCs...
Tissue, Biomaterials, Environment, Cellular, Plastics, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
BMP‐2/TGF‐Β1 GENE INSERTION INTO LIGAMENT‐DERIVED STEM CELLS SHEET PROMOTES TENDON‐BONE HEALING IN A MOUSE
Abstract Bone morphogenetic protein-2 and transforming growth factor-β1 reportedly induce the osteogenic and tenogenic differentiation...
Gene, Protein, Tissue, Genes, Heal, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
AUXOTROPHS COMPROMISE CELL GROWTH AND FATTY ACID PRODUCTION IN SACCHAROMYCES CEREVISIAE
Abstract Auxotrophic marker genes have been widely used for genetic engineering in yeast. However, the effects of amino acids or nucleotides...
Genetic engineering, Gene, Genetics, Engineering, Biosynthesis, Genes, Nucleotides, Nucleotide, Amino acids, General, Research Article -
By Wiley - Jan 26, 2023
A NEAR‐COMPLETE GENOME ASSEMBLY OF BRASSICA RAPA PROVIDES NEW INSIGHTS INTO THE EVOLUTION OF CENTROMERES
Summary Brassica rapa comprises many important cultivated vegetables and oil crops. However, Chiifu v3.0, the current B. rapa reference...
Chromosomes, Genome, Oil, Genomics, Research Article -
By Wiley - Jan 26, 2023
PREDICTING PROTEIN FLEXIBILITY WITH ALPHAFOLD
Abstract AlphaFold2 has revolutionized protein structure prediction from amino-acid sequence. In addition to protein structures, high-resolution...
Environment, Protein, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
A NOVEL QTL GL12 FROM WILD RICE INCREASES GRAIN LENGTH AND WEIGHT IN CULTIVATED RICE
Plant Biotechnology Journal, Accepted Article.
Plant Biotechnology, Plants, BioTechnology, Brief Communication -
By Wiley - Jan 26, 2023
BNAMPK3S PROMOTE ORGAN SIZE BY INTERACTING WITH BNAARF2S IN BRASSICA NAPUS
Plant Biotechnology Journal, Accepted Article.
Plants, Plant Biotechnology, BioTechnology, Brief Communication -
By Wiley - Jan 26, 2023
FIELD TESTING OF TRANSGENIC ASPEN FROM LARGE GREENHOUSE SCREENING IDENTIFIES UNEXPECTED WINNERS
Summary Trees constitute promising renewable feedstocks for biorefinery using biochemical conversion, but their recalcitrance restricts...
Feedstocks, Genes, Chemistry, Industrial, Genetic engineering, Genetics, Gene, Protein, Engineering, Biochemical, Transgenic, Research Article -
By Wiley - Jan 26, 2023
A NOVEL SYNTHETIC SRNA PROMOTING PROTEIN OVEREXPRESSION IN CELL‐FREE SYSTEMS
Abstract Bacterial small RNAs that regulate gene expression have been engineered for uses in synthetic biology and metabolic engineering....
Biology, Metabolic engineering, Applied, Biological, Biologic, Engineering, Genes, Energy, Protein, Gene, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
ADVANCES IN POLYMER‐BASED CELL ENCAPSULATION AND ITS APPLICATIONS IN TISSUE REPAIR
Abstract Cell microencapsulation is a more widely accepted area of biological encapsulation. In most cases, it involves fixing cells...
Biological, Chemicals, Therapeutics, Genetics, Paper, Environment, Immunity, Tissue, Biologic, Cellular, Biology, Chemical, Genetically Modified, REVIEW -
By Wiley - Jan 26, 2023
A CHROMOSOME‐LEVEL GENOME ASSEMBLY OF RADISH REVEALS INSIGHTS INTO GENOME ADAPTATION AND DIFFERENTIAL BOLTING REGULATION
Summary High-quality radish genome represents a valuable resource for agronomical trait improvements and understanding genome evolution...
Protein, Genes, Genomics, Genome, Chromosomes, Gene, Research, Research Article -
By Wiley - Jan 26, 2023
IDENTIFICATION OF TAGL1‐B1 GENE CONTROLLING GRAIN LENGTH THROUGH REGULATION OF JASMONIC ACID IN COMMON WHEAT
Summary Grain length is one of the most important factors in determining wheat yield. Here, a stable QTL for grain length was mapped...
Genes, Genomics, Genome, Chromosomes, Gene, Research Article -
By Wiley - Jan 26, 2023
IN‐SILICO IDENTIFICATION OF TYR232 IN AMPKΑ2 AS A DEPHOSPHORYLATION SITE FOR THE PROTEIN TYROSINE PHOSPHATASE PTP‐PEST
Abstract The AMP-activated protein kinase is known to be activated by the protein tyrosine phosphatase non-receptor type 12 under hypoxic...
Bioinformatic, Protein, Bioinformatics, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
THE C2H2‐TYPE ZINC FINGER TRANSCRIPTION FACTOR OSIC1 POSITIVELY REGULATES STOMATAL CLOSURE UNDER OSMOTIC STRESS IN POPLAR
Summary Salt and drought impair plant osmotic homeostasis and greatly limit plant growth and development. Plants decrease stomatal...
Plants, Transgenic, Gene, Genes, Research Article -
By Wiley - Jan 26, 2023
EXPLORING THE STRUCTURAL AND DYNAMIC DIFFERENCES BETWEEN HUMAN CARNOSINASE I AND II
Abstract Human carnosinases are dimeric dipeptidases in the metallopeptidase M20 family. Two isoforms of carnosinases found in serum...
Neurology, Tissue, Environment, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
LIGANDS‐INDUCED OPEN‐CLOSE CONFORMATIONAL CHANGE DURING DAPE CATALYSIS: INSIGHTS FROM MOLECULAR DYNAMICS SIMULATIONS
Abstract The microbial enzyme DapE plays a critical role in the lysine biosynthetic pathway and is considered as a potentially safe...
Enzymes, Antibiotics, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
NEW SIMULATION INSIGHTS ON THE STRUCTURAL TRANSITION MECHANISM OF BOVINE RHODOPSIN ACTIVATION
Abstract Inactive rhodopsin can absorb photons, which induces different structural transitions that finally activate rhodopsin. We...
Chemicals, Environment, Chemical, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
A NOVEL CONSENSUS‐BASED COMPUTATIONAL PIPELINE FOR SCREENING OF ANTIBODY THERAPEUTICS FOR EFFICACY AGAINST SARS‐COV‐2 VARIANTS OF CONCERN INCLUDING OMICRON VARIANT
Abstract Multiple severe acute respiratory syndrome coronavirus 2 variants continue to evolve carrying flexible amino acid substitutions...
Enzymes, Vaccine, Therapeutics, Computers, Protein, Vaccines, RESEARCH ARTICLE -
By Wiley - Jan 26, 2023
COUNTER‐INTUITIVE ENHANCEMENT OF DEGRADATION OF POLYETHYLENE TEREPHTHALATE THROUGH ENGINEERING OF LOWERED ENZYME BINDING TO SOLID PLASTIC
Abstract Degradation of solid polyethylene terephthalate by leaf branch compost cutinase produces various PET-derived degradation intermediates...
Enzymes, Plastics, Engineering, RESEARCH ARTICLE
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The headlines of BioTech Mag
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
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Cell Culture Associate - InvivoGen - San Diego, CA
We offer an excellent benefits package, which includes medical, dental, vision and life insurance, FSA, paid vacation, profit-sharing and retirement plans (401K... $52,000...
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AIHM declares January Integrative Health Month!
SAN DIEGO, Jan. 26, 2023 /PRNewswire/ - The Academy of Integrative Health officially declares January as Integrative Health Month. AIHM represents 50+ organizations of tens of...
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COVID Virus Ventures Beyond the Lungs, Often Lodging in the Brain
In early 2020, COVID appeared to be mostly respiratory, with blame for the shattering of delicate lung tissues initially placed on the violent “cytokine storms” unleashed from...
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Lost Video of Georges Lemaître, Father of the Big Bang Theory, Recovered
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Companies Already Have the Ability to Decode Your Brainwaves
It wasn't like Duke University futurist Nita Farahany wanted to bring nonstop doom and gloom during her recent “The Battle for Your Brain” presentation at last week's World...
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Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome...
Hepatocellular carcinoma is a leading cause of death globally. Even though the progressive invention of some very potent therapeutics has been seen, the success is limited due...
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Magnetofection of miR-21 promoted by electromagnetic field and iron oxide...
Magnetofection-mediated gene delivery shows great therapeutic potential through the regulation of the direction and degree of differentiation. Lumbar degenerative disc disease...
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Tumor-penetrating nanoplatform with ultrasound “unlocking” for cascade...
Combined therapy based on the effects of cascade reactions of nanoplatforms to combat specific solid tumor microenvironments is considered a cancer treatment strategy with...
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Exosomes derived from human adipose mesenchymal stem cells ameliorate...
Liver fibrosis is a chronic liver disease with the presence of progressive wound healing response caused by liver injury. Currently, there are no approved therapies for liver...
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AI technology generates original proteins from scratch
Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature...