• Evaluation of the Single‐Use Fixed Bed Bioreactors in Scalable Virus Production

    1 month ago - By Wiley

    The accelerating development of gene therapy from research towards clinical trials and beyond has elevated the demand for practical viral vector manufacturing solutions. The use of disposable upstream technology is gaining traction in clinical manufacturing. Packed‐bed or fixed bed reactors, where column is packed with immobilized biocatalyst particles providing surface to constrain the cells in a particular region of the reactor, has been widely used in bioprocessing applications since mid‐1900s. However, the world's first single‐use, fully integrated, high‐cell density fixed‐bed...
    Read more ...