BioTech Mag Search: Virus
In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate
23 days ago - By Springer
Abstract
Objectives
A potent HIV vaccine should overcome some limitations such as polymorphism of human HLA, the diversity of HIV-1 virus, and the lack of an effective delivery system. In this study, a DNA construct encoding Nef 60-84 , Nef 126-144 , Vpr 34-47 , Vpr 60-75 , Gp160 30-53 , Gp160 308-323, and P24 8-151 epitopes was designed using bioinformatics tools. The pcDNA3.1- nef-vpr-gp160-p24 and pcDNA3.1- nef constructs were prepared in large scale as endotoxin-free form. Moreover, the recombinant Nef-Vpr-Gp160-p24 polypeptide and Nef protein were generated in E. coli. These...
Read more ...
Search by Tags
Virus Polymorphisms Vaccines Immunity Protein Vaccine Genes Bioinformatic Bioinformatics DNA Gene
The headlines of BioTech Mag
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Cidara Therapeutics: Research Associate, In Vivo
Cidara Therapeutics: Position Summary Animal technician to conduct in vivo studies in mice at our local vivarium. Will also be required to prepare and work with BSL2 l... San...
Scientists discover how microorganisms evolve cooperative behaviors
New research sheds light on how interspecies interactions arise, evolve and are maintained. The results provide a new window to understand the key roles of these interactions...
Seeing is believing: a visualization toolbox to enhance selection efficiency...
Abstract The emerging and promising biotechnology methodology of CRISPR/Cas9 gene‐editing is revolutionizing crop improvement. However, the low‐efficiency, time‐consuming, and...
Developing a Nicotiana benthamiana transgenic platform for high‐value...
Summary To engineer Nicotiana benthamiana to produce novel diterpenoids, we first aimed to increase production of the diterpenoid precursor geranylgeranyl pyrophosphate by...
Generation of novel self‐incompatible Brassica napus by CRISPR/Cas9
Abstract Self‐incompatibility is a genetic mechanism that prevents inbreeding in hermaphrodite angiosperms via the rejection of self‐pollen. SI lines facilitate the utilization...
Advanced domestication: harnessing the precision of gene editing in crop...
Summary Human population growth has increased the demand for food crops, animal feed, biofuel and biomaterials, all the while climate change is impacting environmental growth...
BlackRock powers Exscientia to $100M series C round to fund autonomous drug...
BlackRock powers Exscientia to $100M series C round to fund autonomous drug design ntaylor Thu, 03/04/2021 - 08:25
Special Issue on AI-driven Informatics, Sensing, Imaging and Big Data...
In this issue, vol. 25, issue 3, March 2021, 1 paper is published related to the Special Issue on AI-driven Informatics, Sensing, Imaging and Big Data Analytics for Fighting...
Prediction of Alzheimer's Disease Progression with Multi-Information...
Alzheimer's disease is a chronic neurodegenerative disease, and its long-term progression prediction is definitely important. The structural Magnetic Resonance Imaging can be...
IEEE EMB DAY! MARCH 5, 2021: STUDENT WORKSHOP ON 3D MODELING AND DESIGN
A partnership between the IEEE Region 2 Women in Engineering and IEEE Engineering in Medicine and Biology, Baltimore Chapter Join the Rowan University WIE Chapter special...