Analysts ponder what Sarepta's whirlwind approval means for Biogen-are all bets off?
After being hit with an FDA rejection for Sarepta Therapeutics' second Duchenne muscular dystrophy drug back in the summer, it looked like a long road, tinged with more than a...
6 minutes ago - Fierce Biotech
New cancer drug targets emerge from massive protein analysis
Baylor researchers scoured all of the proteins present in 500 diverse cancers and made a surprising discovery: All of those cancers, it turns out, can be slotted into 10...
6 minutes ago - Fierce Biotech
Tory landslide election victory sets U.K. on path to Brexit
A thumping election win for the Conservative Party has positioned the U.K. to push ahead with plans to leave the EU. The new parliamentary arithmetic gives Boris Johnson the...
6 minutes ago - Fierce Biotech
Anixa delays CAR-T trial in bid to boost efficacy
Anixa Biosciences has delayed a planned IND filing by 12 months to buy time to improve its CAR-T candidate. The delay will enable Anixa to perform additional genetic...
6 minutes ago - Fierce Biotech
Structural and functional characterization of Solanum tuberosum VDAC36
ABSTRACT As it forms water‐filled channel in the mitochondria outer membrane and diffuses essential metabolites such as NADH and ATP, the VDAC protein family plays a central...
44 minutes ago - Wiley
Prediction of the initial folding sites and the entire folding processes for Ig‐like beta‐sandwich proteins
Abstract Describing the whole story of protein folding is currently the main enigmatic problem in molecular bioinformatics study. Protein folding mechanisms have been...
44 minutes ago - Wiley
The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold
Abstract Trehalose monomycolate represents an essential element of the mycobacterial envelope. While synthesized in the cytoplasm, TMM is transported across the inner membrane...
44 minutes ago - Wiley
Profiling of differentially expressed circular RNAs in peripheral blood mononuclear cells from Alzheimer's disease patients
Abstract Expression of circular RNA , a class of noncoding RNAs that regulates gene expression, is altered in Alzheimer's disease. This study profiled differentially expressed...
46 minutes ago - Springer
Equillium & Biocon Expand Exclusive Licensing Agreement for Itolizumab to Include Australia and New Zealand
LA JOLLA, Calif. and BENGALURU, India, Dec. 12, 2019 - Equillium Inc. , a clinical-stage biotechnology company leveraging deep understanding of immunobiology to develop...
2 hours ago - San Diego Biotechnology
AveXis Inc.: Associate Director, Global Compliance
AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene Durham |...
3 hours ago - San Diego Biotechnology
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
MiRagen Restructures to Focus on Fibrosis, Inks $20M Stock Deal
MicroRNA therapies developer miRagen Therapeutics is scaling back work on its most advanced cancer drug candidate and shifting resources to a compound being developed to treat...
Tiny Quantum Sensors Watch Materials Transform Under Pressure
At left, natural diamonds glow under ultraviolet light owing to their various nitrogen-vacancy centers. At right, a schematic depicting the diamond anvils in action, with NV...
Simulations Attempt to Reconstruct One of the Most Explosive Events in the...
Artist's illustration of two merging neutron stars. The rippling space-time grid represents gravitational waves that travel out from the collision, while the narrow beams show...
Amgen's Osteoporosis Drug Wins European Nod, With a Heart Warning
An osteoporosis drug developed by Amgen now has marketing approval in Europe, but it carries a warning that the medicine can raise the risk of cardiovascular problems...
Aspen Neuro Bags $6.5M to Test Parkinson's Disease Stem Cell Therapy
Nearly nine years ago Jeanne Loring and her colleagues at Scripps Research debuted a test that leveraged advances in genomics and data science to determine, without testing in...
How Thermo Fisher Scientific Streamlined Inspection Management With AuditUtopia®
Case Study Overview In highly regulated industries, you can count on the fact that your company will be inspected a time or two by regulatory agencies and/or your clients. Most...
Cover Picture: Biotechnology Journal 12/2019
Microbial poly‐3‐hydroxybutyrate has been produced via microbial fermentation and safely used as feed additives for sea based large yellow croakers and sensitive land based...
Iterum's Antibiotic for Super Bugs Falls Short in Phase 3, Shares Sink
Iterum Therapeutics' bid to bring patients a new antibiotic that's safer than currently available drugs has fallen short of the main efficacy goal of a late-stage clinical...
A Peek into the Battery Technology Pipeline
Berkeley Lab battery researcher Gerbrand Ceder Lithium ion is probably the most advanced technology available for the packs of rechargeable batteries you'll buy this holiday...
Long-Read Sequencing Could Improve the Sensitivity and Precision of 16S...
It's time to revisit the way scientists are using 16S rRNA gene sequencing to study microorganisms, according to a team of Jackson Laboratory researchers. Popular targets for...