Astin C Production by the Endophytic Fungus Cyanodermella asteris in Planktonic and Immobilized Culture Conditions
The production of astin C, a promising anticancer and anti‐inflammatory compound initially isolated from Aster tataricus, has been recently attributed to its fungal endophyte...
13 minutes ago - Wiley
3D Culture Histology Cryosectioned Well Insert Technology Preserves the Structural Relationship between Cells and Biomaterials for Time‐Lapse Analysis of 3D Cultures
A new cell culture plate well insert is developed for the cryohistology analysis of soft 3D cultures. The 3D‐cryo well insert maintains cell and secreted proteins in their...
13 minutes ago - Wiley
Systems Metabolic Engineering of Escherichia coli Improves Coconversion of Lignocellulose‐Derived Sugars
Systems metabolic engineering approaches involving computational modeling, adaptive evolution, and genome sequencing can be used to develop novel strategies for optimizing...
13 minutes ago - Wiley
Precultures Grown under Fed‐Batch Conditions Increase the Reliability and Reproducibility of High‐Throughput Screening Results
Unintended variations in the inoculum during picking from agar plates lead to unequal growth in the preculture. These variations are passed on to the main culture and influence...
13 minutes ago - Wiley
Free Marine Natural Products Databases for Biotechnology and Bioengineering
Marine organisms and micro‐organisms are a natural source of compounds with unique chemical features, applied in drug discovery, cosmetics, materials, and production of...
13 minutes ago - Wiley
Current Advances in the Utilization of Polydopamine Nanostructures in Biomedical Therapy
The applications of polydopamine for different therapeutic purposes, such as biosensing, bioimaging, drug delivery, antimicrobial, gene delivery and tissue engineering depend...
13 minutes ago - Wiley
Affinity‐Triggered Assemblies Based on a Designed Peptide-Peptide Affinity Pair
WW domains bind to proline‐rich peptides. A small WW peptide is engineered as a minimal version of a full WW domain. The small ligand and the cognate target are conjugated to...
13 minutes ago - Wiley
Novel Promoters Derived from Chinese Hamster Ovary Cells via In Silico and In Vitro Analysis
CHO endogenous promoters and enhancers are identified using histone marks and chromatin states, ranked based on expression level and tested for normalized promoter strength. In...
13 minutes ago - Wiley
Combined Cell Surface Display of β‐d‐Glucosidase , Maltose Transporter , and Overexpression of Cytosolic Xylose Reductase in Saccharomyces cerevisiae Enhance Cellobiose/Xylose Coutilization for Xylitol Bioproduction from Lignocellulosic Biomass
Xylitol is produced from lignocellulosic biomass (rice straw hydrolysate; kraft pulp residues) by a recombinant strain of Saccharomyces cerevisiae. This strain is expressing...
13 minutes ago - Wiley
Mobile‐Phase Modulators as Salt Tolerance Enhancers in Phenylboronate Chromatography: Thermodynamic Evaluation of the Mechanisms Underlying the Adsorption of Monoclonal Antibodies
Flow microcalorimetry has emerged as an online method for the evaluation of adsorptive processes of different molecules. In this work, the adsorption of a anti‐human...
13 minutes ago - Wiley
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2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
2nd International Conference on Generic Drugs and Biosimilars
Nitto BioPharma, Inc: Sr. Scientist, Analytical R&D NBPI031
Nitto BioPharma, Inc: Reporting To: Associate Director, Analytical R&DCore CompetenciesDemonstrated success conducting independent research in areas of analytical chemistry San...
Mapping anatomical related entities to human body parts based on wikipedia...
Background Consisting of dictated free-text documents such as discharge summaries, medical narratives are widely used in medical natural language processing. Relationships...
USC in San Diego - after a bitter battle, moving forward
USC's Alzheimer's Therapeutic Research Institute manages critical therapy trials...
USC and UC San Diego try to move on after painful fight over Alzheimer's...
Both schools say they're found a way to prosper while studying the inscrutable disease...
Characterization and mechanism of the effects of Mg-Fe layered double...
Layered double hydroxides have received widespread attention for their potential applications in catalysis, polymer nanocomposites, pharmaceuticals, and sensors. Here, the...
VIST - a Variant-Information Search Tool for precision oncology
Diagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient's genome. This analysis relies on previously...
RF Purify: a novel tool for comprehensive analysis of tumor-purity in...
With the advent of array-based techniques to measure methylation levels in primary tumor samples, systematic investigations of methylomes have widely been performed on a large...
Multitask learning for biomedical named entity recognition with...
Biomedical named entity recognition is a fundamental and essential task for biomedical literature mining, which affects the performance of downstream tasks. Most BioNER models...
Semiparametric estimation in regression with missing covariates using...
Abstract We investigate semiparametric estimation of regression coefficients through generalized estimating equations with single-index models when some covariates are missing...
Genetic relatedness and its causal role in the evolution of insect societies
Abstract The role of genetic relatedness in social evolution has recently come under critical attention. These arguments are here critically analyzed, both theoretically and...